The design, development, and experimental validation of an inductively-powered optical neuro-stimulator integrated circuit (IC) with on-chip neural recording, temperature monitoring, signal processing, and bidirectional wireless data communication are presented. The microLED stimulation circuit can linearly drive 0.1-10mA currents with only 150mV required headroom (smallest reported in literature). The current amplifier yields constant gain for the entire output current range, even under large supply voltage variations. The IC is fabricated in a standard 130nm CMOS process. Measurement results for different sensory/communication blocks are presented, as well as in-vitro experimental validation results showing simultaneous optical stimulation, electrical recording, and calcium imaging.