This work presents a novel process to embed an active silicon chip into a PCB for integrated microfluidic applications. The integration process is fast, affordable, and makes use of standard equipment and materials. It is ideal for quick prototyping but could also eventually be adapted for mass production since it is compatible with industrial technologies. A significant benefit of the proposed method is the ability to directly combine heterogeneous components, whether they be microfluidic, microelectromechanical, or electronic, within an integrated, compact system. This platform aims to serve as a further step towards realizing intelligent lab-on-a-chip systems.