The experience of using project-based learning (PBL) methods is talked about in the context of training STEM (science, technology, engineering, and math) students for the real-world scenarios in the industry. In this paper, a PBL strategy is proposed as a pedagogical tool targeting undergraduate computer science, CS+[X] — where [X] may range from health-science to robotics and intelligent systems, engineering students through the design of a biomedical imaging system for breast cancer detection. The primary goals of this interdisciplinary project are, firstly, to train students to implement the theoretical knowledge towards design of engineering product directly targeting one or more sustainable development goals. During the design and implementation of this project, students’ competencies have improved significantly which reassures the usefulness of PBL as a pedagogical approach in student-centered learning under the framework of outcome-based education.