A key role in the efficient functionality of the qubit control/readout system plays the mixed-signal circuits, with Analog-to-Digital converters (ADCs) and Digital-to-Analog converters (DACs) being the dominant blocks for uniting the analog and digital domain. CMOS technology has been proven to be a promising candidate for implementing such circuits and achieving efficient cryogenic operation at 4 K, simultaneously meeting speed, critical performance characteristics’, and power requirements. This work overviews the state-of-the-art DAC and ADC cryo-CMOS circuit implementations for quantum computing and discusses the challenges and future strategic steps that are henceforth required for the development of scalable next-generation quantum computers.