A novel charge sharing technique is presented to mitigate electrode DC offsets in a DC-coupled biomedical resettable electrode readout front-end. Allowing the working electrodes to share charge with the reference electrode via a brief periodic reset attenuates the electrode offsets while drawing safe levels of DC currents from the electrodes. Simulations for the example of neural readout have shown how the offset range can be reduced to about ±2mV for a reset time of 1us for a broad span of electrode parameters. The area and power overhead due to offset cancellation hardware can be completely eliminated through the use of this technique.