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Video s3
    Details
    Presenter(s)
    Liyang Wang Headshot
    Display Name
    Liyang Wang
    Affiliation
    Affiliation
    University of Macau
    Country
    Country
    Macao SAR China
    Author(s)
    Display Name
    Liyang Wang
    Affiliation
    Affiliation
    University of Macau
    Display Name
    Sio-Hang Pun
    Affiliation
    Affiliation
    University of Macau
    Display Name
    Peng Un Mak
    Affiliation
    Affiliation
    University of Macau
    Display Name
    Achim Klug
    Affiliation
    Affiliation
    University of Colorado School of Medicine
    Display Name
    Bai-Jun Zhang
    Affiliation
    Affiliation
    Sun Yat-Sen University
    Display Name
    Mang I Vai
    Affiliation
    Affiliation
    University of Macau
    Display Name
    Tim Lei
    Affiliation
    Affiliation
    University of Colorado Denver
    Abstract

    This paper presents a Correlational Combination (CC) algorithm and its hardware implementation to be used in future multi-channel real-time spike sorting systems. Preprocessing of neural spikes are required to eliminate duplication for neural spikes recorded from a neural probe with densely spaced recording channels. In this work, we proposed using Pearson's correlation to identify duplicated neural spikes and to combine them selectively to improve SNR for a representative spike prior to performing spike sorting. Other approaches (Single Selection and Average All) were also compared with simulated multi-channel neural spikes and CC has the highest SNR for both software and hardware implementations. A hardware implementation of the CC algorithm was realized with a Xilinx Zynq-UltraScale+ field programmable gate array (FPGA). A SNR improvement of 93% was achieved when compared to the other approaches. A processing latency of 1.58µs for the CC hardware module was achieved when a 250MHz system clock was used to drive the FPGA.

    Slides
    • A real-time correlational combination algorithm to improve SNR for multi-channel neural recordings (application/pdf)