In this paper we have presented an automated and centralized data generation and hybrid acquisition system. First of all, we have described its various modules: high-level hardware covering the internal FPGA logic (including interfacing options) and the digital and analog parts; and the software aspect covering both the firmware alternatives and the PC interfacing options. The generation and acquisition methodology has been detailed revealing data flow procedures and relevant information extraction. Experimental results have been exposed using a special hardware setup and a specific testing scenario. The collected data showed equally important data synchronization, data alignment and cycle-accurate analog measurements using pseudo-random bit sequences at the HSDO. Also, we have compiled a comparative table showing main differences between the presented system and related work. Finally, we have showed the added value, the planned future work and the need of such a specially tailored instrument, initially as an efficient alternative of the main features of three different off-the-shelf instruments and also as an automated, programmable and cost-efficient piece of hardware.