We propose a high accurate and high energy-efficient Absolute-Difference-Accumulation Operation Computing-In-Memory processor that with two key features: 1) computation reuse for low-power, resulting in a 49.5% CIM operation power reduction, and 2) low-cost sign prediction core with 3-bit activation and weight quantization for high utilization. From the two key features, the proposed ADA-CIM processor is simulated in 28 nm CMOS technology and occupies 3.78 mm2. It consumes 2.77 mW and achieves 43.1 TOPS/W energy-efficiency with a high-accuracy of 91.62% at CIFAR-10 (ResNet-20) increasing 42% energy-efficiency than previous high-accurate-and-efficient CIM with 91.5% accuracy and 30.4 TOPS/W.