This paper discusses about Mixed Signal Design Verification Methodology (MSDV) which has been adopted for verifying Ambient Light Sensor (ALS) Interface. Analog sub blocks used within the system are modelled using SystemVerilog. Block level verification is done by performing equivalence checks between Analog schematics and behavioral models with the help of self-checking testbenches. The entire process of block level verification is well automated by means of script-based regressions.