Nowadays distributed electronic health and fitness monitoring are hot-topics in bio-engineering, however common solutions for Wireless Body Area Networks (WBANs) featuring high-density sampled data transmission still stumbles over the trade-off among data rate, application throughput, and latency. Therefore, the Bluetooth Low Energy (BLE) and the IEEE 802.15.4 protocols are here investigated, with the aim of developing an event-driven WBAN to support a threshold-crossing surface ElectroMyoGraphy (sEMG) acquisition approach. We then implemented a custom protocol to overcome their limitations and fulfil all the requirements, resulting in a transmission latency of 0.856 ms ± 1 μs and enabling a functional operating time up to 110 h.