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AffiliationInterdisciplinary Institute for Technological Innovation, Université de Sherbrooke
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A low-power and low-noise bioamplifier for multi-channel electrode arrays (MEA) is presented. Reduction in area and power is achieved by implementing an active lowpass filter without large DC-blocking capacitors, and by employing a modern CMOS technology. As the main building block of a 49-channel bioamplifier array designed in TSMC 28 nm CMOS, this bioamplifier has been designed to amplify, filter out the unwanted noise and, extract the action potentials of neural signals. This paper presents a theoretical analysis of noise and power reduction in addition to proposing design tradeoffs. The amplifier occupies an area of 0.003 mm2 and consumes 4.6 µW from a 1.8 V power supply. Based on post-layout simulation results, the power, area and noise specification of the proposed design is comparable with the best performance reported to date. The bioamplifier achieves a mid-band gain of 55 dB, a -3 dB bandwidth from 450 Hz to 9.2 kHz and input-referred noise on this bandwidth is 10 µVrms.